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Newswise — Irvine, Calif., Aug. 21, 2019 — Scientists from the University of California, Irvine School of Biological Sciences have discovered how to forestall Alzheimer’s disease in a laboratory setting, a finding that could one day help in devising targeted drugs that prevent it.
The researchers found that by removing brain immune cells known as microglia from rodent models of Alzheimer’s disease, beta-amyloid plaques – the hallmark pathology of AD – never formed. Their study appears in the journal Nature Communications. (Link to study: https://www.nature.com/articles/s41467-019-11674-z)
Previous research has shown most Alzheimer’s risk genes are turned on in microglia, suggesting these cells play a role in the…
