Concordance between the assessment of Aβ42, T-tau, and P-T181-tau in peripheral blood neuronal-derived exosomes and cerebrospinal fluid

Jump to Section1. Introduction2. Methods and materials  2.1. Participants  2.2. Collection of neuronal-derived exosomes from blood  2.3. Transmission electron microscopy  2.4. Western blot  2.5. Collection of CSF  2.6. Protein measurements  2.7. Statistical analysis3. Results  3.1. Participant characteristics  3.2. Confirmation of exosomal collection  3.3. Levels of Aβ42, T-tau, and P-T181-tau in blood neuronal-derived exosomes and CSF  3.4. Biomarker correlation analysis between blood neuronal-derived exosomes and CSF  3.5. Diagnostic power of each biomarker in blood neuronal-derived exosomes and CSF  3.6. Composite biomarkers4. DiscussionSupplementary DataReferences

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