A research team including faculty at Binghamton University and University of Colorado Denver are the first to map the molecular structure of an aggressive protein aggregate that causes acceleration of Alzheimer’s disease.
“Approximately 10 percent of Alzheimer’s cases result from familial mutations,” said Wei Qiang, assistant professor of biophysical chemistry at Binghamton University. “The other 90 percent cases are caused by misfolded wild-type amyloid proteins. We need to understand the molecular basis of the disease pathology. In doing so, we might one day create drugs that prevent the degenerative effects of the disease.”
Alzheimer’s disease starts developing when toxic…
