Using imputation to provide harmonized longitudinal measures of cognition across AIBL and ADNI
DatasetsThis study utilized neuropsychological, clinical, demographic and neuroimaging data collected as part of the AIBL and ADNI studies. The process of recruitment and enrolment in each of these studies has been described in detail...
#UCSFRadGrateful Gives Kudos to Our People in 2021
The UCSF Department of Radiology and Biomedical Imaging is pleased to launch our 2021 gratitude campaign on social media (#UCSFRadGrateful). We recently invited our wonderful nurses, techs, faculty, staff and...
Researchers use virtual reality to learn about bodily consciousness — ScienceDaily
Scientists and philosophers have pondered the nature of consciousness for centuries. But now, researchers from Japan have uncovered new information that challenges previous theories about the relationship between two elements of consciousness.
In a study...
Structure of pathological TDP-43 filaments from ALS with FTLD
1.Neumann, M. et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314, 130–133 (2006).ADS
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Long-term dynamics of aberrant neuronal activity in awake Alzheimer’s disease transgenic mice
To address the question whether neuronal activity is altered in awake APPPS1 mice and if so, how stable these aberrant activity levels are, we longitudinally monitored the activity of the same identified neurons in...
-324x235.jpg "Six Highlights from UCSF Radiology at RSNA21!")
Six Highlights from UCSF Radiology at RSNA21!
After Thanksgiving each year, the UC San Francisco Department of Radiology and Biomedical Imaging looks forward to the Radiological Society of North American (RSNA) Annual Meeting. This year’s event was...
New optical technology spotlights how memories move in mouse brains during sleep — ScienceDaily
When an important document lands on your desk, you might file it away for safekeeping. The same thing happens with our memories: they first appear in one part of the brain and then move...
A deep learning framework identifies dimensional representations of Alzheimer’s Disease from brain structure
Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, PA, USAZhijian Yang, Ilya M. Nasrallah, Haochang Shou, Junhao Wen, Jimit Doshi, Mohamad Habes, Guray Erus, Ahmed Abdulkadir, David A. Wolk, Christos Davatzikos, Yong Fan, Vishnu Bashyam, Elizabeth Mamouiran, Randa Melhem, Raymond Pomponio, Dushyant Sahoo, Singh Ashish, Ioanna Skampardoni, Lasya Sreepada, Dhivya...
Unveiling the hidden cellular logistics of memory storage in neurons — ScienceDaily
Exploring the mechanisms involved in sleep-dependent memory storage, a team of University of Michigan (U-M) cellular biologists found that RNAs associated with an understudied cell compartment in hippocampal neurons vary greatly between sleeping and...
Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early...
We found that sCoV increased between SCD, MCI and early probable AD groups in GM and in the temporal lobe. As expected, sCoV was negatively correlated with CBF. Overall, our results suggest that sCoV...
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Take it from the rats: A junk food diet can cause long-term damage to...
A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...
Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Degenerative Dementias and Their Medical Care in the Movies
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...