Potential new treatment for Alzheimer’s disease would be relatively cheap — ScienceDaily
Researchers at the RIKEN Center for Brain Science (CBS) in Japan have discovered that the protein α-endosulfine (ENSA) is involved in the development of Alzheimer's disease. Studies in mice showed that eliminating this protein...
The effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the...
1.Renton, A. E. et al. A Hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 72, 257–268 (2011).CAS
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Brain region called the anterior thalamus could hold the key for memory function recovery...
The mammalian brain houses a complex network of structures that support memory, and a small region called the anterior thalamus is a critical part of this system. Damage to the mammillothalamic tract (MTT) --...
Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence
Selective APPswe expression in OB-lineage cells in TgAPP
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The Significance of the Recently Published ACC/AHA Chest Pain Guidelines
The American College of Cardiology (ACC)/American Heart Association (AHA) recently published their ACC/AHA Chest Pain Guidelines. This marks the first update to these official clinical practice guidelines in nearly a...
Association of tear fluid amyloid and tau levels with disease severity and neurodegeneration
ParticipantsA total of 56 patients and nine cognitively healthy controls (HC) were enrolled in this study. Patients were recruited from the BioBank Alzheimer Center Limburg (BB-ACL), Maastricht, the Netherlands. Inclusion criteria were an MMSE...
Cultural Diversity in Alzheimer Disease: The Interface between Biology, Belief, and Behavior
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Falls and Physical Activity in Persons With Mild to Moderate Dementia Participating in an...
Background:
Physical activity is beneficial in people with dementia. As physical activity increases risk exposure for falls, safety concerns arise. Prior exercise trials in people with dementia have not measured physical activity. Falls in...
Association between depression and the risk of Alzheimer’s disease using the Korean National Health...
1.Livingston, G. et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet 396, 413–446. https://doi.org/10.1016/S0140-6736(20)30367-6 (2020).Article
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Effects of the Tailored Activity Program in Brazil (TAP-BR) for Persons With Dementia: A...
Objectives:
The objectives of this study were to evaluate the effects of the Tailored Activity Program—Brazilian version (TAP-BR), on behavioral symptoms and the quality of life (QOL) in persons with dementia, as well as...
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Take it from the rats: A junk food diet can cause long-term damage to...
A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...
Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Degenerative Dementias and Their Medical Care in the Movies
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...