CEO David R. Weinreb of The Howard Hughes Corporation Honored for Support of Alzheimer’s...
The Alzheimer's Drug Discovery Foundation Ninth Annual Fall Symposium & Luncheon Raises Record-Breaking Total of Over $1.6 Million
Ronald S. Lauder, David R. Weinreb, Alice Shure, Leonard A. Lauder,...
Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and...
MaterialsAntibodies for p65, p-p65, BDNF, claudin-5, occludin, caludin-1, iNOS, COX-2, and β-actin were purchased from Cell Signaling Technology (Beverly, MA). Enzyme-linked immunosorbent assay (ELISA) kits for cytokines were purchased from Ebioscience (San Diego, CA)....
Survey Insights Help Capture Why Referring Physicians Choose UCSF Radiology
Author: Laurel Skurko, former Marketing Director, UCSF Radiology and Biomedical Imaging
The UCSF Radiology marketing team is grateful to Bay Area referrers who have provided their feedback regarding customer service needs...
Profound degeneration of wake-promoting neurons in Alzheimer’s disease
Fig. 2Representative histological images of wake-promoting nuclei. LC (top), LHA (middle), and TMN (bottom) tissue sections are depicted with their corresponding neurotransmitter/enzymes (TH, orexin, or HDC, respectively; in red) and tau (CP13; in brown). Notice...
The ADDF’s Diagnostics Accelerator Initiative Expands Its Focus on Frontotemporal Degeneration
A Partnership with The Association for Frontotemporal Degeneration
The Alzheimer's Drug Discovery Foundation's (ADDF) Diagnostics Accelerator initiative has announced a new $5 million commitment to projects targeting the development...
HENA, heterogeneous network-based data set for Alzheimer’s disease
Transformation-based integration overviewBringing together individual data types undoubtedly enriches the systematic view on the Alzheimer’s disease, giving researchers the opportunity to understand molecular mechanisms from the genetic to protein levels. However, it also involves...
UCSF Radiology Welcomes New Faculty Members
The UC San Francisco Department of Radiology and Biomedical Imaging would like to extend a warm welcome to our talented incoming faculty members. We are proud of their accomplishments and...
Neuropsychological latent classes at enrollment and postmortem neuropathology
Brain autopsies of 779 decedents were examined. Baseline latent class analysis on 10 neuropsychological measures was previously assigned: mixed-domains impairment (n = 39, 5%), memory-specific impairment (n = 210, 27%), frontal impairment (n = 113, 14.5%), average cognition (n =...
New Generation of Therapeutics Based on Understanding of Aging Biology Show Promise for Alzheimer’s
A scientific strategy that explores therapeutic targets based on the biology of aging is gaining ground as an effective approach to prevent and treat Alzheimer's disease, according to...
Acute restraint stress reverses impaired LTP in the hippocampal CA1 region in mouse models...
Acute stress rescues impaired LTP in the hippocampal CA1 region of AD miceIn the first set of experiments, we determined whether acute stress alters LTP in the CA1 region by recording fEPSPs in acutely...
Latest article
Take it from the rats: A junk food diet can cause long-term damage to...
A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...
Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Degenerative Dementias and Their Medical Care in the Movies
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...