Sunday, May 5, 2024

Marital Relationship Quality in Early-Stage Dementia: Perspectives From People With Dementia and Their Spouses

Spouse caregivers of people with dementia (PwD) report relatively poor marital relationship quality (RQ), but few studies have obtained the perspective of the PwD, examined discrepancies between spouses, or considered changes in RQ over...

Meet the Duo Researching the Application of Augmented Reality Technology for Improved Patient Care...

During surgical planning conference, Jesse Courtier, MD noticed a recurring challenge – surgeons often have difficulty translating radiology information into real-world patient care for surgical planning. As a pediatric radiologist and...

Relationship between dementia and gut microbiome-associated metabolites: a cross-sectional study in Japan

Study designThis study was a sub-analysis of data from the gerontological investigation of microbiome: a longitudinal estimation study (the Gimlet study) at the National Center for Geriatrics and Gerontology (NCGG)4. The present sub-analysis study...

Characterization of lactic acid bacteria derived exopolysaccharides for use as a defined neuroprotective agent...

The identification of the isolates was done via sequencing each one’s 16 S rRNA gene region, resulting in the amplification of a fragment of 1492 bp. The isolates were shown to be lactobacilli and were ≥...

C9orf72 suppresses systemic and neural inflammation induced by gut bacteria

1.DeJesus-Hernandez, M. et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 72, 245–256 (2011).2.Majounie, E. et al. Frequency of the C9orf72 hexanucleotide repeat expansion in...

A Comparison Study of Mild Cognitive Impairment With 3 Memory Tests Among Chinese Individuals

Objective To examine whether 3 common memory tests differ statistically in terms of mild cognitive impairment (MCI) discrimination rates and conversion rates to Alzheimer disease. Methods A sample of 329 Chinese patients who consulted our...

N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer’s disease

Molecular dockingMolecular modeling studies were performed using Discovery Studio Programs (2018, Accelrys) and figures were generated using PyMOL programs. The 3D coordinates of human SphK1 complexed with ADP were obtained from the protein data...

Neuropathologic Correlates of Activities of Daily Living in Alzheimer Disease

Abstract: Functional status, reflected by measures of activities of daily living (ADLs), deteriorates as Alzheimer disease (AD) progresses. Decline in activities of daily living may be mediated by executive and frontal lobe dysfunction. The objective...

Lindsay Lawless, RN is a 2020 Daisy Award Recipient

We are in the middle of celebrating Nurses Week here at the UCSF Department of Radiology and Biomedical Imaging. This observance was started by the American Nurses Association to celebrate...
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Take it from the rats: A junk food diet can cause long-term damage to...

A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...

Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature

The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...

Degenerative Dementias and Their Medical Care in the Movies

Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...