Study in mice finds potential therapy to reverse memory loss from Alzheimer’s

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Credit: Unsplash/CC0 Public Domain

Researchers from Macquarie University have discovered a world-first new treatment that reverses the effects of memory loss associated with Alzheimer’s disease in a study of mice with advanced dementia.

The research, co-led by two brothers, Dr. Arne Ittner and Professor Lars Ittner, from Macquarie University Dementia Research Center, builds on their work begun in 2016 involving a ground-breaking gene therapy which uses an enzyme that is naturally present in the brain, known as p38gamma.

The researchers found that p38gamma, when activated, can modify a protein such that it prevents the development of Alzheimer’s disease…

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