University of Warwick researchers have developed a superior method to describe the very earliest effects that Alzheimer’s Disease proteins have on the properties of brain cells.
In the paper “Introduction of Tau oligomers into cortical neurons alters action potential dynamics and disrupts synaptic transmission and plasticity,” published in the journal eNeuro, researchers directly identify new therapeutic targets and describe a new standard for future research activity.
Alzheimer’s disease is characterised by the accumulation of Amyloid beta plaques outside neurons and the build-up of Tau protein inside neurons. Tau protein normally contributes to neuronal stability and…
