New imaging tool helps researchers see extent of Alzheimer’s early damage

Alzheimer's disease
PET scan of a human brain with Alzheimer’s disease. Credit: public domain

New imaging technology allows scientists to see the widespread loss of brain synapses in early stages of Alzheimer’s disease, a finding that one day may help aid in drug development, according to a new Yale University study.

The research, published May 13 in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, compared the density of synapses, which transmit signals between neighboring , in people with early stages of Alzheimer’s with those of people who have no evidence of the disease. As expected, the loss of synapses in those with an early stage of Alzheimer’s was particularly high in areas…

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