Scientists find functioning amyloid in healthy brain

Scientists find functioning amyloid in healthy brain
Protein FXR1, extracted from the brain of healthy rats, is colourised with an amyloid specific dye ‘Congo Red’ and shows an apple-green glow in polarised light, which is recognised as the ‘gold standard’ for amyloid identification. Credit: St. Petersburg State University

Scientists from St Petersburg University worked with their colleagues from the St Petersburg branch of the Vavilov Institute of General Genetics. They conducted experiments on laboratory rats and showed that the FRX1 protein in the brains of young and healthy animals functions in an amyloid form. The previously published reports indicate that this protein controls long term memory and emotions: mice that have the FRX1 gene “off” quickly remember even complex mazes, and animals that have too much of this protein do not suffer from depression even after…

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