Researchers have discovered a potential drug target for Alzheimer’s disease—an enzyme which has effects on both the immune and nervous systems.
Dr. Ramón Martínez-Mármol and Professor Frédéric A. Meunier from the Queensland Brain Institute Clem Jones Centre for Ageing Dementia Research found that targeting one enzyme could combat the disease on two fronts.
“In nerve cells, the enzyme dPI3K produces a toxic peptide which accumulates into plaques in the brain of Alzheimer’s disease patients, causing havoc,” Dr. Martínez-Mármol said.
“Our study shows that the enzyme is also involved in the secretion of one of the most important signaling proteins involved in…
