Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer’s disease, researchers from the University of Pittsburgh School of Medicine reveal in a paper published today in Nature Medicine.
For the first time ever, the researchers showed in living patients that neuroinflammation—or activation of the brain’s resident immune cells, called microglial cells—is not merely a consequence of disease…
