Escitalopram for agitation in Alzheimer’s disease (S-CitAD): Methods and design of an investigator-initiated, randomized,...
Conflicts of interest: D.P.D. reports consulting for Eisai, Acadia, and Avanir. L.S.S. reports grants from NIA and the State of California, within 3 years and during the conduct of the study; grants from Eli Lilly,...
The role of astrocytic α7 nicotinic acetylcholine receptors in Alzheimer disease
Davies, P. & Maloney, A. J. Selective loss of central cholinergic neurons in Alzheimer’s disease. Lancet 2, 1403 (1976).Article
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UCSF Radiologists Lead Work on SAR/ESUR Joint Consensus Statement for MR Imaging of Placenta...
Placenta accreta spectrum (PAS) disorders have become a significant life-threatening disease with rising incidence and high maternal-fetal morbidity and mortality. Imaging plays a crucial role in prenatal detection of these...
Events serve as ‘stepping stones’ en route to retrieved memories — ScienceDaily
One solution to this frustratingly common scenario is to retrace your steps. This can be done by physically moving through the space where you suspect your elusive keychain is hiding or, as explored in...
Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards...
Data sourcesThe data used in the study are from two large-scale EHR databases: the Research Patient Data Registry in the United States at Mass General Brigham Healthcare (US RPDR) and the Clinical Practice Research...
Understanding of novel functional roles can advance research in Alzheimer’s disease, other learning and...
A research team led by University of California, Irvine has discovered new neural circuits that regulate spatial learning and memory in the brain's hippocampal formation. The team identified novel functional roles of new circuit...
Factors Influencing Appraisal of Upset in Black Caregivers of Persons With Alzheimer Disease and...
Abstract:
Black caregivers of persons with Alzheimer disease and related dementias (ADRD) have demonstrated significantly lower levels of stress and burden than white caregivers, as measured by instruments that assess caregiving burden and stressfulness of...
Marcia Gay Harden Honored at Hope on the Horizon Women’s Luncheon in Palm Beach
The Alzheimer's Drug Discovery Foundation (ADDF) honored actress, author, and advocate Marcia Gay Harden at its Hope on the Horizon Luncheon held at The Colony in Palm Beach...
Hippocampal subfield vulnerability to α-synuclein pathology precedes neurodegeneration and cognitive dysfunction
Goedert, M., Spillantini, M. G., Tredici, K. D. & Braak, H. 100 years of Lewy pathology. Nat. Rev. Neurol. 9, 13 (2013).Article
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Early Impairment in the Ventral Visual Pathway Can Predict Conversion to Dementia in Patients...
Background:
Around 15% to 20% of patients with clinically probable Alzheimer disease have been found to have no significant Alzheimer pathology on amyloid positron emission tomography. A previous study showed that conversion to dementia...
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Take it from the rats: A junk food diet can cause long-term damage to...
A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...
Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Degenerative Dementias and Their Medical Care in the Movies
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...