In the present study, we found that Aβ− patients with major-VCD displayed more nonamnestic cognitive impairments than Aβ+ patients with major VCD. Moreover, independent of disease severity, Aβ− patients showed more depressive symptoms than Aβ+ patients with VCD. Mild VCD Aβ+ patients showed less WMH than Aβ− patients. However, in patients with major VCD, Aβ+ patients…