Researchers find unanticipated complexity in aging brain’s memory decline

Researchers from The University of Texas at Dallas Center for Vital Longevity (CVL) have discovered that brain correlates of age-related memory decline are more complicated than previously believed, a finding that could affect efforts to preserve cognitive health in older people.

Dr. Michael Rugg, CVL director and professor of psychology in the School of Behavioral and Brain Sciences, is the senior author of a study, published online Nov. 30 and in the Jan. 24 print edition of The Journal of Neuroscience, that found that age-related neural dedifferentiation, marked by a decline in the functional specialization of different brain regions, is driven by multiple mechanisms.

As people age — even in good health — the brain becomes less precise in how different classes of visual information are represented in the visual cortex. This reduction in neural selectivity, or dedifferentiation,…

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