Natural compounds derived from soy and other plants reduce breast cancer recurrence and improve survival

Soy compounds called isoflavones are among the plant-derived compounds that may significantly reduce the risk of breast cancer recurrence or death, according to a new meta-analysis co-directed by investigators from the Johns Hopkins Kimmel Cancer Center. The results were published Jan. 10 in the journal JNCI Cancer Spectrum.

Investigators in Australia, Denmark, England, Norway and the U.S. reviewed 22 published observational studies that examined the impact of dietary intake of soybeans, lignans (compounds found in a variety of plants including seeds and nuts), cruciferous/cabbage-family vegetables, and green tea — and these substances’ phytonutrients (natural compounds derived from plants) — on breast cancer recurrence and mortality, as well as on mortality from all causes. This included 11 studies of soy isoflavones, three of cruciferous vegetables, two of green tea, three of…

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