Metal-based molecules show promise against the build-up of Alzheimer’s peptides

Metal-based molecules show promise against the build-up of Alzheimer’s peptides
Image of mouse brain highlighting the areas where one of the metal complexes under study accumulates. Credit: Imperial College London

In lab tests, Imperial researchers have created a metal-based molecule that inhibits the build-up of a peptide associated with Alzheimer’s disease.

A peptide is a fragment of a protein, and one of the key hallmarks of Alzheimer’s disease is the build-up of a specific peptide known as amyloid-β. The team demonstrated that with the aid of ultrasound, their molecule can cross the in mice, targeting the part of the where the damaging peptide most often accumulates.

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