Recent Study Identifies 11 Candidate Genetic Variants for Alzheimer’s Disease

Newswise — LEXINGTON, Ky. (July 13, 2021) — A recently published study co-authored by University of Kentucky Sanders-Brown Center on Aging researcher Justin Miller, Ph.D., identifies 11 rare candidate variants for Alzheimer’s disease. Researchers found 19 different families in Utah that suffered from Alzheimer’s disease more frequently than what is considered normal.

Miller, an assistant professor in the UK College of Medicine, was a co-first author for the study published in the journal Alzheimer’s & Dementia. The work was started at another university, however, some of the computational work was done after Miller arrived at UK in March.  

For the study, genetic sequencing was conducted on two cousins from each of the 19 families. Miller says they then identified genetic variants that were shared between both cousins.

“We then used a series of filtering criteria to…

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