Summary:
Twenty-four subjects with Alzheimer disease underwent cognitive and functional assessment. Functional assessment by caregivers consisted of a 25-item bipolar analog scale measuring activities of daily living and social behaviors divided into four functional domains: memory, attention/executive abilities, everyday skills, and self-care. Cognitive assessment consisted of standardized neuropsychological tests designed to evaluate five cognitive domains: episodic memory, attention/executive function, semantic memory, visuospatial function, and auditory–verbal short-term (working) memory. Functional assessment correlated well with overall severity as measured by Mini Mental State Examination (r = −0.733). Analysis of individual cognitive and functional domains revealed no significant correlation between episodic memory and functional performance. By contrast, functional…
Home Alzheimer's Research Relationship Between Functional and Neuropsychological Performance in Early Alzheimer Disease
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