BMI1, a promising gene to protect against Alzheimer’s disease

BMI1, a promising gene to protect against Alzheimer's disease
Healthy neurons (left) and Alzheimer’s disease neurons (right): in green, accumulation of G4 structures in Alzheimer’s neurons. Credit: University of Montreal

Another step towards understanding Alzheimer’s disease has been taken at the Maisonneuve-Rosemont Hospital Research Centre. Molecular biologist Gilbert Bernier, and professor of neurosciences at Université de Montréal, has discovered a new function for the BMI1 gene, which is known to inhibit brain aging. The results of his work have just been published in Nature Communications.

In his , Bernier was able to establish that BMI1 was required to prevent the DNA of neurons from…

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