SuperAger brains resist protein tangles that lead to Alzheimer’s

brain
Credit: Unsplash/CC0 Public Domain

A new Northwestern Medicine study showed cognitive SuperAgers have resistance to the development of fibrous tangles in a brain region related to memory and which are known to be markers of Alzheimer’s disease.

The tangles are made of the which forms structures that transport nutrients within the nerve cell. These tangles disrupt the cell’s transport system, hampering communication within the neuron and preventing nutrients from performing their particular job within the cell. The end result of tangle formation is cell death.

“The results suggest resistance to age-related tau degeneration in the cortex may be one…

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