Automated imaging detects and tracks brain protein involved in Alzheimer’s disease

Newswise — BOSTON – Amyloid-beta and tau are the two key abnormal protein deposits that accumulate in the brain during the development of Alzheimer’s disease, and detecting their buildup at an early stage may allow clinicians to intervene before the condition has a chance to take hold. A team led by investigators at Massachusetts General Hospital (MGH) has now developed an automated method that can identify and track the development of harmful tau deposits in a patient’s brain. The research, which is published in Science Translational Medicine, could lead to earlier diagnoses of Alzheimer’s disease.

“While our understanding of Alzheimer’s disease has increased greatly in recent years, many attempts to treat the condition so far have failed, possibly because medical interventions have taken place after the stage at which the brain injury becomes irreversible,” says lead…

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