Sex-specific Alzheimer’s treatment could benefit males over females

Sex-specific Alzheimer's treatment could benefit males over females
Post-mortem brain tissue reveals the memory function in female and male Alzheimer’s mice differed after they were treated with a drug that selectively blocks a receptor to regulate memory and learning. Credit: University of Ottawa

A University of Ottawa study has found a specific Alzheimer’s treatment is effective in male and not female mice, providing a window into the biology of the disease and the effectiveness of targeted treatments.

The paper, ‘AB oligomers induce pathophysiological mGluR5 signaling in Alzheimer’s model in a sex-selective manner,’ published in Science Signaling Magazine highlights the mechanisms underlying Alzheimer’s disease…

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