Comorbid amyloid-β pathology affects clinical and imaging features in VCD

In the present study, we found that Aβ− patients with major-VCD displayed more nonamnestic cognitive impairments than Aβ+ patients with major VCD. Moreover, independent of disease severity, Aβ− patients showed more depressive symptoms than Aβ+ patients with VCD. Mild VCD Aβ+ patients showed less WMH than Aβ− patients. However, in patients with major VCD, Aβ+ patients…

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