A research framework for cognitive aging and Alzheimer’s disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos—Investigation of Neurocognitive Aging (SOL-INCA)

Fig. 2

SOL-INCA MCI diagnostic schema. Participants with MCI diagnosis must have (1) significant self-reported cognitive decline (eCog-12); (2) low age-, sex-, education-, and PVT-adjusted absolute cognitive test scores relative to SOL-INCA internal normative ranges, and significant global cognitive decline in test performances of at least −0.055 SD yearly; and (3) no to mild functional impairment (IADLs, e.g., managing medications). Abbreviations: SR, self-reported; SD, standard deviation; MCI, mild cognitive impairment; NC, neurocognitive; IADL, Instrumental Activity of Daily Living; eCog, everyday cognition; PVT, Picture Vocabulary Test; SOL-INCA, Study of Latinos–Investigation of Neurocognitive Aging.

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