Neuroscientists at the University of Southampton have made a significant development in understanding how Alzheimer’s disease spreads through the brain, discovering a significant period of time where medical intervention could halt its onset.
A hallmark of Alzheimer’s disease is the accumulation of tau protein in neurons which causes loss of brain volume. This build up, known as neurofibrillary tangles, is formed when a diseased version of tau folds itself incorrectly. Prior to this research, published today in the Journal of Neuroscience, very little was known about the timescale of this process and how the misfolded tau…
