An oral anticoagulant delays the appearance of Alzheimer’s disease in mice

An oral anticoagulant delays the appearance of Alzheimer's disease in mice
Cells of the immune system (red) cross from the cerebral blood vessels (green) to infiltrate the brain of a mouse with Alzheimer disease. Chronic treatment with dabigatran impedes this process and reduces disease symptoms. Credit: CNIC

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a possible treatment for Alzheimer’s disease. Working together with a scientific team at the Rockefeller University in New York, the investigators have shown that treatment with the oral anticoagulant dabigatran delays the appearance of Alzheimer’s disease in mice.

The results published today in the Journal of the American College of Cardiology (JACC) show that after a year of…

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