MEDIA CONTACT
Available for logged-in reporters only
- Aggregates of Tau protein in the brain are a hallmark of neurodegeneration, particularly in Alzheimer’s disease.
- Researchers at the University of Warwick have introduced fluorescently labelled Tau aggregates (oligomers) into single brain neurons and were able to track their movement and effects.
- They found the introduced Tau oligomers interfered with the action potential waveform, modified the strength of neuronal communication and blocked events that underlie memory storage by mis-localising to synapses.
- Preventing Tau from oligomerising could be a new therapeutic target for Alzheimer’s disease
University of Warwick researchers have developed a superior method to describe the very earliest effects that Alzheimer’s Disease…
