Study used videos of realistic activities to measure how memory works day to day...
You might remember you ate cereal for breakfast but forget the color of the bowl. Or recall watching your partner put the milk away but can't remember on which shelf.
A new Northwestern Medicine study...
Alzheimer disease | Nature Reviews Disease Primers
1.Jessen, F. et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease. Alzheimers Dement. 10, 844–852 (2014).PubMed
PubMed Central
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Disease-associated astrocytes in Alzheimer’s disease and aging
1.Keren-Shaul, H. et al. A unique microglia type associated with restricting development of Alzheimer’s disease. Cell 169, 1276–1290.e17 (2017).2.Strooper, B. & Karran, E. The cellular phase of Alzheimer’s disease. Cell 164, 603–615 (2016).3.Baruch, K....
Synergistic depletion of gut microbial consortia, but not individual antibiotics, reduces amyloidosis in APPPS1-21...
Animal housing and handlingAPPPS1-21 mice in a C57BL6Cj background were obtained from M. Jucker (University of Tubingen, Tubingen, Germany) and were housed in the animal research center facility at the University of Chicago. Mice...
A high-generalizability machine learning framework for predicting the progression of Alzheimer’s disease using limited...
Datasets used in the studyThe data used for training, cross-validation, and test in our study were obtained from the ADNI1, ADNI-GO, and ADNI2 datasets in the NA-ADNI database (http://adni.loni.usc.edu/ADNI). The NA-ADNI is a cohort...
High Hemoglobin A1c and Diabetes Predict Memory Decline in the Health and Retirement Study
Background:
Type 2 diabetes (T2D) is an established risk factor for dementia, but evidence for T2D and memory decline is less consistent. Understanding how T2D and blood glucose relate to memory decline is crucial...
Study shows that the larger an image, the better we remember it — ScienceDaily
Every day we encounter images on the wall, in newspapers, books, and electronic devices. Some become etched in our memory and some don't. The elements influencing whether we remember one image and not the...
A needle for Alzheimer’s in a haystack of claims data
A needle for Alzheimer’s in a haystack of claims data
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Transcriptomic analyses reveal proinflammatory activation of human brain microvascular endothelial cells by aging-associated peptide...
Global transcriptional changes induced by medin, Aβ, and NL in HBMVECsTo investigate molecular impact of medin on HBMVECs, three independent sets of seven treatment groups of HBMVECs were prepared and analyzed by RNA-seq, which...
Prostate Artery Embolization (PAE): A Physician’s Perspective
Prostate artery embolization (PAE) is a minimally-invasive therapy offered at UCSF by interventional radiology physicians to patients suffering from severe symptoms of prostate enlargement, otherwise known as benign prostatic hyperplasia (BPH)....
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Take it from the rats: A junk food diet can cause long-term damage to...
A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...
Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Degenerative Dementias and Their Medical Care in the Movies
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...