Urinary metabolic phenotyping for Alzheimer’s disease
1.Hampel, H. et al. Perspective on future role of biological markers in clinical therapy trials of Alzheimer’s disease: A long-range point of view beyond 2020. Biochem. Pharmacol. 88, 426–449. https://doi.org/10.1016/j.bcp.2013.11.009 (2014).CAS
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-High-Quality-324x235.jpg "UCSF Radiology Residents Shine at RSNA20")
UCSF Radiology Residents Shine at RSNA20
Last week, the Radiological Society of North America (RSNA) held their annual meeting completely virtually. One of the positives of this was that registration was free for all RSNA members....
Visual short-term memory is more complex than previously assumed — ScienceDaily
Contrary to previous assumptions, visual short-term memory is not merely based on one kind of information about an object, such as only its colour or only its name. Rather, several types of information can...
Studies could lead to new ways to enhance memory for those with traumatic brain...
Two studies led by UT Southwestern researchers shed new light on how the brain encodes time and place into memories. The findings, published recently in PNAS and Science, not only add to the body...
Cognitive impairment is associated with mitochondrial dysfunction in peripheral blood mononuclear cells of elderly...
Participants in this studyThe present study is a cross-sectional study, and it was approved by the Committee on Human Rights Related to Research Involving Human Subjects, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand...
Increasing the reproducibility of fluid biomarker studies in neurodegenerative studies
There are many potential sources of poor reproducibility for biomarker studies. These include cohort-related factors, pre-analytical factors, analytical and kit-related factors, biotemporal variability of the measured markers, insufficient statistical methods, lack of proper validation,...
Proton pump inhibitors and the risk of Alzheimer’s disease and non-Alzheimer’s dementias
We evaluated the risk of PPI use and the incidence of AD and other types of dementia in a community-based retrospective cohort. We considered at least a five-year lag window between the start of...
Applying the Alzheimer Disease ATN Diagnostic Framework in Atypical Dementia
Cerebrospinal fluid (CSF) biomarkers amyloid-β and tau have been validated for the antemortem diagnosis of Alzheimer disease (AD) and are included in the AT(N) research framework for AD. Recently, an AT(N) CSF profile has...
Abnormal cortical thickening and thinning in idiopathic normal-pressure hydrocephalus
1.Relkin, N., Marmarou, A., Klinge, P., Bergsneider, M. & Black, P. M. Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery 57(Suppl. 3), S4-16. https://doi.org/10.1227/01.neu.0000168185.29659.c5 (2005).Article
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Feasibility and Accuracy of Different Methods for Collecting Data on Falls Among Older People...
This study compared different methods for collecting data on falls among people with dementia to identify which is most feasible and accurate. Eighty-three dyads, comprised of a community-dwelling person with dementia and their informal...
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Take it from the rats: A junk food diet can cause long-term damage to...
A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may...
Repurposing non-pharmacological interventions for Alzheimer’s disease through link prediction on biomedical literature
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Degenerative Dementias and Their Medical Care in the Movies
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...