Disrupted circadian regulation of cognition in Alzheimer’s disease

Disrupted circadian regulation of cognition in Alzheimer’s disease
We know about circadian regulation of sleep, but new research in a mouse model of Alzheimer’s disease suggests beta-amyloid buildup in the brain could also contribute to deficits in circadian regulation of learning and memory early in the disease process. Credit: Shutterstock.com

Circadian dysfunction linked to Alzheimer’s disease is known to disrupt sleep and daily activity patterns. New research in a mouse model of the disease suggests beta-amyloid buildup in the brain, one of the hallmarks of Alzheimer’s disease, could also contribute to deficits in circadian regulation of learning and memory early in the disease process.

Researchers tested cognitive…

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