Scientists find promising avenue to restore cognitive function impaired by Alzheimer’s disease

Scientists find promising avenue to restore cognitive function impaired by Alzheimer's disease
The compound ISRIB shrank plaques in the brain in a mouse model of Alzheimer’s disease (right, rectangle). Credit: M.M. Oliveira et al., Science Signaling (2021)

A team of neuroscientists has identified a potential means to address the loss of cognitive function due to Alzheimer’s disease by targeting protein synthesis in mice. Their findings, reported in the journal Science Signaling, reveal that synthetic pharmaceuticals could rescue the activity of brain cells needed for memory formation.

“This work is the first to show that reversing impaired in brains afflicted by Alzheimer’s disease through a pharmacological approach is not only…

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