Study targets gene associated with Alzheimer’s disease

Study targets gene associated with Alzheimer’s disease
The neurons in this image are stained blue, indicating the presence of the BIN1 protein. Points of direct interaction between BIN1 and calcium channels are in purple. Credit: University of Alabama at Birmingham

Researchers at the University of Alabama at Birmingham are on the track of a gene that might play a role in the development of Alzheimer’s disease. The research team is studying a gene called BIN1, which was first linked to Alzheimer’s disease in 2009.

In a paper recently published online in eLife, the team shows that BIN1 helps to regulate the activity of neurons. This may be significant, as too much neuronal activity, known as hyperexcitability, is…

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