Researchers identify two marine molecules with therapy potential against Alzheimer’s disease

Alzheimer's disease
PET scan of a human brain with Alzheimer’s disease. Credit: public domain

An interdisciplinary research study of the University of Barcelona identified two potential candidates to treat Alzheimer’s disease. These are two marine molecules, meridianine and lignarenone B, able to alter the activity of GSK3B activity, a protein associated with several neurodegenerative diseases.

The researchers used several biocomputational techniques to detect these so far unknown compounds, which were later validated with experiments in cultures of neuronal cells in mice. These results will allow researchers to better understand the functioning of the GSK3B molecule and build a promising starting point for the…

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