Simple molecular reagents to treat Alzheimer’s disease

Simple molecular reagents to treat Alzheimer’s disease
Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors found in the Alzheimer’s disease-affected brain and the chemical series studied in this work. Credit: The Korea Advanced Institute of Science and Technology (KAIST)

Sometimes the most complex problems actually have very simple solutions. A group of South Korean researchers reported an efficient and effective redox-based strategy for incorporating multiple functions into simple molecular reagents against neurodegenerative disorders. The team developed redox-active aromatic molecular reagents with a simple structural composition that can simultaneously target and modulate various pathogenic factors in complex neurodegenerative disorders such as Alzheimer’s disease.

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