Sleep-disordered breathing tied to brain changes

Sleep-disordered breathing tied to brain changes

(HealthDay)—Sleep-disordered breathing (SDB) is associated with changes in the brain, including amyloid deposition in brain regions typically involved in Alzheimer disease, according to a study published online March 23 in JAMA Neurology.

Claire André, Ph.D., from Université de Caen in France, and colleagues used data from 127 community-dwelling older adults (mean age, 69.1 years; 63 percent women) participating in the Age-Well randomized clinical trial (2016 to 2018). The analysis included participants who underwent neuropsychological assessment, polysomnography, magnetic resonance imaging, and florbetapir and fluorodeoxyglucose positron emission tomography. The authors sought to determine whether the presence of SDB…

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