Arterial stiffening linked to Alzheimer’s disease

blood vessel
Credit: Pixabay/CC0 Public Domain

A research team from Vanderbilt University Medical Center reports in Neurology that greater stiffening of the aorta, the main artery in the human body, is associated in older adults with increased Alzheimer’s disease (AD) pathology as reflected in a range of neurochemical indicators measured in cerebrospinal fluid.

“These results have major implications for Alzheimer’s disease prevention,” said Angela Jefferson, Ph.D., professor of Neurology and founding director of the Vanderbilt Memory and Alzheimer’s Center, who led the study with Elizabeth Moore, an MD/Ph.D. student who recently completed a Ph.D. under Jefferson’s…

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