New research may offer hope for Alzheimer’s patients

Newswise — LEXINGTON, Ky. (June 4, 2021) — University of Kentucky Department of Neuroscience Professor Greg Gerhardt, Ph.D., hypothesizes that the balance of glutamate and gamma-aminobutyric acid (GABA) — two main neurotransmitters in the brain — contributes to Alzheimer’s disease and age-related declines in cognition and memory.

Now, the UK College of Medicine researcher and his team are about to find out. Gerhardt has developed new technology that can simultaneously measure the two neurotransmitters on a second-by-second basis. It is the first time this will be done in vivo — or in the living brain of awake animals. 

Thanks to a five-year, $2 million grant from the National Institute on Aging, Gerhardt is launching a study to explore the balance of GABA and glutamate in the aging brain. The program will provide answers to long-standing questions that…

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