The drainage network in a mouse’s brain is outlined in blue and green, and dotted with clumps of the Alzheimer’s protein amyloid beta (red). Researchers at Washington University School of Medicine in St. Louis have found that improving the function of the network, known as the meningeal lymphatics, can make certain experimental Alzheimer’s therapies more effective in mice. Credit: Sandro Da Mesquita
Experimental Alzheimer’s drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations. But new research in mice has shown that some investigational Alzheimer’s therapies are more effective when paired with a treatment geared toward improving drainage of fluid—and debris—from the brain, according to a study led by researchers at…
The complete workflow is depicted in Fig. 1. To investigate the association between NPIs and AD, we initially conducted preprocessing and integration of biomedical triples...
Compared with other neurologic problems, few films have been dedicated to degenerative dementia. To our knowledge, this is the first systematic review about the...
