Experimental drug shows potential against Alzheimer’s disease

Experimental drug shows potential against Alzheimer's disease
Chaperone-mediated autophagy in a neuron: A protein chaperone (red circle) escorting a molecule of damaged tau protein (green) docks with a LAMP2 receptor (blue) on the cell’s lysosome (orange) and pushes the tau protein inside the lysosome, where it is digested. Credit: Albert Einstein College of Medicine

Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer’s disease in mice. The drug works by reinvigorating a cellular cleaning mechanism that gets rid of unwanted proteins by digesting and recycling them. The study was published online today in the journal Cell.

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