Study leads to potential for new treatment approach to Alzheimer’s

University of Ky study leads to potential for new treatment approach to Alzheimer's
Donna Wilcock, of the Sanders-Brown Center for aging in her lab on August 14, 2019. Credit: Mark Cornelison | UKphoto

Research looking at a possible new therapeutic approach for Alzheimer’s disease was recently published in the Journal of Neuroinflammation. The paper out of the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) is titled “Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition”. The work looked at targeting inflammation by using an antibody. Alzheimer’s disease and related dementias have no disease-modifying treatments at this time and represent a looming public health crisis given the continually growing aging population.

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