Gene variant staves off Alzheimer’s in some people, scientists find

Alzheimer's disease
Diagram of the brain of a person with Alzheimer’s Disease. Credit: Wikipedia/public domain.

People with a gene variant that puts them at high risk for Alzheimer’s disease are protected from its debilitating effects if they also carry a variant of a completely different gene, Stanford University School of Medicine investigators report in a large new study.

Their findings, to be published Apr. 13 in JAMA Neurology, suggest that a substantial fraction of the estimated 15% of Americans carrying the high-risk are protected to some degree from Alzheimer’s disease by a variant of the other gene. (A gene will often come in a variety of versions, or variants, that can produce different…

Read more…