If we can overcome the loss of a process in the brain called “RNA editing,” we may be able to slow the progress of Alzheimer’s disease and other synaptic disorders, a new study has shown.
RNA editing is a genetic mechanism that modifies proteins essential in the connection between nerve cells in the brain, called synapses. RNA editing is deregulated in the brains of people with Alzheimer’s disease, but whether this can cause disease is unknown.
In this study, the scientific team at the University of Technology Sydney Centre for Neuroscience & Regenerative Medicine (CNRM) replicated this deregulated process in the brains of mice, and discovered it led to the loss of…
