Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD

Plasma BACE1 concentration is a novel core candidate biomarker potentially serving for different context(s) of use to enrich both clinical diagnostic-prognostic workup and pharmacological trials for early Aβ-targeted therapies for AD. To investigate the question whether and how BACE1 expression levels (reflected by plasma concentrations) are…

Read more…