Alzheimer's Biology 101 (7 Minutes)

7 minute course on the basic biology, chemistry and genetics behind Alzheimer’s. How does Alzheimer’s happen? What is going on in the brain? This video will bring you up to speed.

What is Alzheimer’s disease? Alzheimer’s (Alzheimer) disease is a neurodegenerative disease that leads to symptoms of dementia. It involves an accumulation of beta-amyloid plaque and neurofibrillary tangles in the brain. This video covers the mechanisms and pathophysiology thought to contribute to Alzheimer’s disease, including a definitions of sporadic as well as familial Alzheimer’s.

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This video is provided by AlzheimersWeekly.com under a Creative Commons License from Osmosis.org. Osmosis offers a comprehensive e-learning platform that connects med students with thousands of flashcards and quiz questions, depending on each student’s needs. Ever wish information would just diffuse into your brain? Well, Osmosis helps make that possible—don’t learn it, osmose it!

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Resources:
http://www.ncbi.nlm.nih.gov/pmc/artic…
http://emedicine.medscape.com/article…
http://www.uptodate.com/contents/clin…
https://en.wikipedia.org/wiki/Alzheim…

Credits:
Script/audio/visuals: Tanner Marshall, MS
Reviewer: Rishi Desai, MD, MPH

Attributions:
Beta amyloid plaque histology by ‘Jensflorian’ – https://commons.wikimedia.org/wiki/Fi…
Neurofibrillary tangles histology by ‘Nephron’ – https://commons.wikimedia.org/wiki/Fi…
Sword slash attack sound effect by Iwan Gabovitch – https://www.freesound.org/people/qubo…
Cargo train sound effect by Stephan Schutze – http://soundbible.com/1874-Cargo-Trai…