Novel discovery of links between liver dysfunction and Alzheimer’s disease

Novel discovery of links between liver dysfunction and Alzheimer's disease
Andrew J. Saykin, PsyD, is director of the Indiana Alzheimer Disease Center at Indiana University School of Medicine. Credit: IU School of Medicine

New research from the Alzheimer’s Disease Metabolomics Consortium (ADMC) and Alzheimer’s Disease Neuroimaging Initiative (ADNI) has uncovered novel connections between liver dysfunction and Alzheimer’s disease (AD), paving a new path toward a systems level view of Alzheimer’s relevant for early detection and ultimately for prevention.

The study, published today in JAMA Network Open was led by IU School of Medicine radiology professor Kwangsik Nho, Ph.D. and explores the relationship between blood-based biochemical markers of function and established…

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